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Introduction : Right hemicolectomy and ileocecal resections are common colorectal procedures, typically indicated for the management of right colorectal cancer (RCC) and Crohn’s disease. These interventions can give rise to postoperative events; of which the most life-threatening is the anastomotic leak (AL). Observation of the last decade shows that the complication rate for this type of operation seems not to be decreasing. The aim of this survey is to objectify the complication rate in patients operated in the Cliniques universitaires Saint-Luc (CUSL) for right hemicolectomies and ileocecal resections and compare the results between two groups of population which are right colon cancer and Crohn’s disease. Methods: Data of patients operated in the CUSL for right hemicolectomies and ileocecal resections between 2007 and 2011 have been collected. Several parameters have been included and organized into categories which are demographic information, preoperative data (including symptoms, surgical approach,…), follow-up and postoperative data including complication rate and histological features. Results: 178 patients have been operated for right hemicolectomies or ileocecal resections with 30,33% (54) of them for Crohn’s disease and 60,11% (107) for RCC. The mean ae for these 2 groups was 36,80 and 70,25 years –old respectively 38,89% (21) of the Crohn’s patients and 21,50% (23) of the RCC were smokers. The most frequent symptom (33,64) after anemia (34,57) in the RCC patients. The main surgical approach was laparoscopy in the Crohn patients (75, 93 %) while laparotomy was as frequently used (47,66 %) as the laparoscopic approach (52,34 %) in the RCC patients. The immediate postoperative complication rate was 9, 55% for all the patients, with 14, 81 % of the Crohn patients having complications and 8,41% out of the CRR group. The AL rate was 3, 93% (7/178) out of all the operations, with 6 of them in Crohn patients and 1 in a RCC patient. Conclusion: Right hemicolectomies and ileocecal resections are operations that can give rise to a major postoperative complication which is the AL and this one remains a challenge for the surgeon. Its rate at the CUSL is low with 3,93% out of all the interventions and comparison between our 2 groups indicates that Crohn patients are at a higher risk than RCC patients for developing this kind of complication. Introduction : Les résections coliques droites et iléo-caecales sont des interventions courantes de chirurgie colorectale indiquées principalement dans la prise en charge du cancer du côlon droit (CCR) et de la maladie de Crohn. Ces interventions courantes peuvent se compliquer d’événements post-opératoires dont le plus redoutable est la fuite de l’anastomose (FA). Il ressort des observations des dernières années que le taux de complications pour ce type d’opération ne semble pas diminuer. L’objectif de ce travail de recherche est d’objectiver le taux de complications chez les patients opérés aux CUSL pour résections coliques droites et iléo-caecales et de comparer les résultats entre deux groupes de population que sont le cancer du côlon droit et la maladie de Crohn. Matériel et méthodes : les dossiers de patients opérés aux CUSL pour résections coliques droites et iléo-caecales entre 2007 et 2011 ont été passés en revue. Différents paramètres ont été collectés et classés en catégories que sont les données démographiques, données préopératoires et opératoires, données préopératoires et opératoires, données de suivi postopératoire en ce inclus le taux de complications et les caractéristiques anatomopathologies. Résultats : 178 patients ont été opérés pour résections coliques droites ou iléo-caecales dont 30,33% (54) pour la maladie de Crohn et 60,11% (107) pour CRR. L’âge moyen pour ces 2 groupes a été de 36,80 et 70,25 ans respectivement 38,89% (21) des patients de Crohn et 21,50% (23) des CCR ont été fumeurs. Le symptôme le plus fréquent chez les patients Crohn (75,93 %) alors que ce symptôme était le second le plus fréquent (33,64) chez les patients CCR après l’anémie (34,57%). La voie d’abord de choix a été la laparoscopie chez les patients Crohn (75,93 %) tandis que la laparotomie était presqu’aussi fréquente (47,66%) que la laparoscopie (52,34%) pour les patients CCR. Le taux de complications immédiates a été de 9,55 % pour tous les patients, avec 14,81% pour les patients Crohn et 8,41 % pour les CCR. Au total, le taux de FA a été de3,93% (7/178) toutes interventions confondues, dont 6 survenues chez des patients Crohn et 1 dans le cas d’un CCR. Conclusion : les résections coliques droites et iléocæcales sont des interventions dont la complication majeure est la FA et celle-ci reste un défi pour le chirurgien. Son taux aux CUSL est bas avec 3,93% et la comparaison entre ces deux groupes de patients nous indique que les patients de Crohn sont plus à risque de ce genre de complications que les patients CCR.

Endoscopic Mucosal Resection --- Crohn Disease

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

inflammation --- innate cells --- mucosal pathology --- mediators --- homeostasis

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Immunology --- lung infection and pathology --- mucosal inflammation --- epithelial barrier function --- mucosal immune response --- therapeutic interventions

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This textbook is primarily intended for students of dental medicine, it can also be useful for the students of general medicine whom it can help in clinical and field practice. The term “diseases of the oral mucosa” describes a diverse group of diseases of various aetiologies and seriousness and this issue is closely related to dermatovenerological, otorhinolaryngological, ophthalmological, rheumatological and internal diseases. The dentist may often be the first physician noticing and possibly diagnosing a general disease based on symptoms of the oral cavity. The new extended edition reflects the improving knowledge of the etiopathological processes of oral mucosal diseases on the molecular level and the ever increasing range of diagnostic laboratory tests and/or therapeutic options.

Dentistry --- oral mucosal diseases --- clinical picture --- differential diagnosis --- treatment

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Immunology --- inflammation --- innate cells --- mucosal pathology --- mediators --- homeostasis